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CYSTORELIN is indicated for the treatment of ovarian follicular cysts in dairy cattle. Ovarian cysts are non-ovulated follicles with incomplete luteinization which result in nymphomania or irregular estrus. Historically, cystic ovaries have responded to an exogenous source of luteinizing hormone (LH) such as human chorionic gonadotropin. CYSTORELIN initiates release of endogenous LH to cause ovulation and luteinization.
CYSTORELIN was the first-selling GnRH productapproved by the FDA for treatment of cystic ovaries in cattle. CYSTORELIN is labeled for use in combination with SYNCHSURE to synchronize estrous cycles to allow for fixed-time artificial insemination (FTAI) in lactating dairy cows and beef cows.
IMPORTANT SAFETY INFORMATION FOR CYSTORELIN: DO NOT USE IN HUMANS. KEEP THIS AND ALL DRUGS OUT OF THE REACH OF CHILDREN.
IMPORTANT SAFETY INFORMATION FOR SYNCHSURE: FOR ANIMAL USE ONLY, NOT FOR HUMAN USE. KEEP OUT OF REACH OF CHILDREN. Women of childbearing age, asthmatics, and persons with bronchial and other respiratory problems should exercise extreme caution when handling this product. In the early stages women may be unaware of their pregnancies. SYNCHSURE™ (cloprostenol sodium) is readily absorbed through the skin and may cause abortion and/or bronchospasms: direct contact with the skin should therefore be avoided. Accidental spillage on the skin should be washed off immediately with soap and water.